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Hootone Remedies is an Indian pharmaceutical firm registered with FDA and manufacturing according to cGPM Standard Specifications, following the traditional time proven Indigenous Indian ethics of Unani-Ayurvedic system in concurrence with the most modern medical findings, exercising our own innovative techniques for developing drugs for the dreaded diseases like AIDS, Cancer, Leukemia, Hepatitis, Kidney failure, Heart problems & Liver diseases etc confronting the cotemporary world.
Hootone Remedies aims at researching & developing herbal drugs, especially the life saving ones not available in any other system at present and our R&D wing had several landmark achievements to its credit, like formulating the most outstanding anti-retroviral herbal drug HOO-IMM PLUS which recorded 98% inhibition in invitro test.
HOO-IMM PLUS, a plant based dual target HIV drug, works by inhibiting 2 different enzymes that are critical for HIV replication; (IN) Integrase & (RT) Reverse Transcriptase, thus prevent the virus from replicating and spreading throughout the body and reduce the risk of drug resistance that overall improves the treatment outcome.
Invitro IC50 values, measured for HOO-IMM PLUS was the lowest in micro molar concentration against integrase and Reverse transcriptase viral enzymes indicating their potency against the viral enzymes.
Invitro anti-HIV assays, determine the HOO-IMM PLUS activity against 3'processing reaction of integrase enzymes making HOO-IMM PLUS one such kind of 3'processing inhibitor, works by blocking the enzyme called HIV integrase, responsible for the integration of viral DNA into human genome. The 3' processing inhibition leads to the decline in the integrated viral DNA leading to innovative strategic cure therapy.
5 way actions to combat HIV with the New HOO-IMM PLUS:-
1) Successive Viral Decay (Decline in Latent Viral Reservoir - HIV Proviral DNA)
2) No Virological failure (No Viral RNA rebound).
3) Successive CD4 cell recovery (Improves CD4/CD8 ratio).
4) Prevents against Opportunistic Infections (OIs)
5) Productive & Quality Life.
The New upgraded HOO-IMM PLUS had undergone the invitro anti-HIV colorimetric test in order to determine the percent inhibition of the drug against the (RT) Reverse Transcriptase that is very important target of HIV.
The kit used for the above test is as under:
1) HIV-1 reverse transcriptase Assay (Xpress Bio, USA)
The IC50 for the New Upgraded HOO-IMM PLUS was recorded at 0.950 µM against the most preferred ARVs (EFA) which is 1.472 µM
The New upgraded HOO-IMM PLUS had undergone the invitro anti-HIV colorimetric test in order to determine the percent inhibition of the drug against the (IN) Integrase that is very important target of HIV.
The kit used for the above test is as under:
1) HIV-1 integrase Assay for Non Catalytic inhibitor (Xpress Bio, USA)
The IC50 of the New Upgraded HOO-IMM PLUS for the Integrase Non Catalytic Assay was recorded at 1.46 µM against the most preffered ARVs (EVG) which had recorded no inhibition at all for the Integrase Non Catalytic Assay
A drug that regulates the immune response. HOO-IMM PLUS helps to restore the balance of the immune system by restoring the CD4 T-cells in HIV patient which is otherwise low due to viral attack.
The New Upgraded HOO-IMM PLUS treatment regulates 10-20 % of overall CD4 T-cells.
Biomarker Test : CD4 / CD8 count
ARVs inability to long term suppress the virus results in increase in viral RNA load. "The No Virologic Failure" ability of HOO-IMM PLUS effectively results the patient's viral load at undetectable level; a positive outcome of patient receiving HOO-IMM PLUS over ARVs.
Biomarker Test : HIV RNA Quantitative
A process in which a virus gradually losses its ability to replicate and spread over the time. Its an important factor in controlling and eventually eliminating HIV infection.
With the New Upgraded HOO-IMM PLUS treatment accelerate the rate of viral decay. This has been observed in patient with decline proviral DNA (infected CD4 cells/ cell associated HIV DNA).
Biomarker Test :HIV-1 Proviral DNA Quantitative & Qualitative Test
Invitro anti-HIV assays, determine the HOO-IMM PLUS activity against 3'processing reaction of integrase enzymes making HOO-IMM PLUS one such kind of 3'processing inhibitor, works by blocking the enzyme called HIV integrase, responsible for the integration of viral DNA into human genome. The 3' processing inhibition leads to the decline in the integrated viral DNA leading to innovative strategic cure therapy.
Invitro Clinically Tested : The 3' processing inhibition of the New Upgraded HOO-IMM PLUS was measured and evaluated through the Integrase Non Catalytic Assay with Xpress Bio, USA
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Its incredibly a great results in my patient, so happy
The patient got a very good viral inhibition to undetectable level with Hooimm plus.
My patient improved significantly with CD4 count around 1236 and viral load count below 40 copies
Bandra, Mumbai, India
+91 9594000093
info@hootone.org